AD Neuropathology in those with APOE e2/e2 alleles

 
   Lead Investigator:    Marwan Sabbagh
   Institution      :    Arizona Alzheimers Center
   E-Mail           :    Marwan.Sabbagh@dignityhealth.org
   Proposal ID      :    846


   Publications:


1  Stipho F, Jackson R, Sabbagh MN
   Pathologically confirmed AD in ApoE ^{unicode 03b5}2 homozygotes is rare but does occur
   Journal Article  J Alzheimers Dis,62:1527-1530,2018,PMC29562509

   PUBLISHED



2  Stipho F, Jackson R, Sabbagh MN
   Pathologically Confirmed AD in ApoE ^{unicode 03b5}2 Homozygotes is Rare but Does Occur
   Abstract  AAIC 2018,7:P1292-1293,2018,

   PUBLISHED





   Proposal Description:
   The specific aims  of this study:                                                 (1) to confirm that Apo E 2/2 can be associated with AD pathology                 (2) to estimate the prevalence of Apo E 2/2 in an autopsy defined AD cohort       (3) to estimate the  of AD pathology in Apo E 2/2 carriers                        (4) to characterize the AD cases with Apo E 2/2